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CHEMISTRY

Katie Mitchell-Koch

KatieMitchell-Koch

Title: Assistant Professor of Chemistry

Education: Ph.D., University of Kansas

Research Area: Physical and Theoretical Chemistry

Phone: 316-978-7371

Fax: 316-978-3431

E-mail: katie.mitchell-koch@wichita.edu

Mitchell-Koch Group Home Page

Principal Research Interests

Solvent dynamics in enzyme active sites
We use computational methods to answer questions such as:

  • How does the environment around the enzyme active site influence solvent dynamics?
  • What are the hydrogen bond lifetimes of substrates and solvents within enzymes?
  • Why do different solvents yield different products in solvent-compatible enzymes?

Representative Publications

  1. Anthony A. Vartia, Katie R. Mitchell-Koch, Guillaume Stirnemann, Damien Laage, and Ward H. Thompson, “On the Reorientation and Hydrogen-Bond Dynamics of Alcohols” J. Phys. Chem. B, 2011, 115 (42), 12173–12178.
  2. Katie R. Mitchell-Koch and Ward H. Thompson, “Infrared Spectra of a Model Phenol-Amine Proton Transfer Complex in Nanoconfined CH3Cl” J. Phys. Chem. B, 2008, 112 (25), 7448–7459.
  3. Katie R. Mitchell-Koch and Ward H. Thompson, “How Important is Entropy in Determining the Position-Dependent Free Energy of a Solute in a Nanoconfined Solvent?”, J. Phys. Chem. C, 2007, 111 (32), 11991–12001.